Journal: Scientific Reports

Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

doi: 10.1038/s41598-024-78332-3

Figure Lengend Snippet: Overview of experiments and mice used for the respective experiments.

Article Snippet: The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands).

Techniques: Biomarker Discovery

Journal: Scientific Reports

Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

doi: 10.1038/s41598-024-78332-3

Figure Lengend Snippet: Schematic overview of experimental protocols and setup for each experiment. ( A ) Graphic illustration of timeline and study design for experiment 1–3. ( B ) Picture of LABORAS test cages. ( C ) Picture of burrowing tube in test cage. NB. Pictures do not represent the experimental light conditions. Created with BioRender.com.

Article Snippet: The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands).

Techniques:

Journal: Scientific Reports

Article Title: The search for non-evoked markers of pain in the GTN mouse model of migraine

doi: 10.1038/s41598-024-78332-3

Figure Lengend Snippet: Data summary from Experiment 1 and 2. A) Von Frey test was performed before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 16/group, individual values and mean ± SEM. B-D) 4 h LABORAS data obtained from same mice as in A on days 1, 5, 7, and 9 immediately after GTN injection. No effect of GTN, but increased activity when testing during the dark phase (day 5), day effect p < 0.0001, Two-way repeated ANOVA. E-F) Von Frey data days 1–9 before (basal) and 2 h after i.p. injection of GTN 10 mg/kg or its vehicle, mixed effect model with Bonferroni post hoc comparison between groups, n = 12/group, mean ± SEM. G-H) Locomotion and distance traveled on day 11 with a 60 min delay of LABORAS initiation after GTN injection. Same mice as in E-F, students t-test.

Article Snippet: The LABORAS setup consisted of LABORAS test boxes resembling home cages (22 × 16 × 14 cm), situated on the LABORAS platforms connected to a computer and LABORAS software-v2.6.9 (Metris B.V, The Netherlands).

Techniques: Injection, Comparison, Activity Assay

Journal: Molecules

Article Title: Effects of Peppermint Essential Oil on Learning and Memory Ability in APP/PS1 Transgenic Mice

doi: 10.3390/molecules27072051

Figure Lengend Snippet: Levels of oxidative stress factors in brain tissues of each group of mice ( x ¯ ± S , n = 8).

Article Snippet: Total protein (BCA) test box, MDA, SOD, and GSH-PX test box were purchased from Nanjing Jiancheng Biological Engineering Institute (Nanjing, China).

Techniques: Mouse Assay